In 2023, Aspram Avanesyan graduated from the Journalism Department of Artsakh State University. From 2021 to 2023, she participated in the "Media Literacy" course organized by the Media Initiatives Center.
She began her professional career at Artsakh Public Radio, where she worked as a journalist-commentator from December 2020 to July 2023. She completed an internship at the "Or" news program of Artsakh Public Television in September 2023, before the forced displacement. From June 2023 until its closure in March 2025, she freelanced for the "Voice of America." Following the displacement, from November 2023 to June 2024, she was one of the journalists for the "Hayrenakits" program on Armenian Public Television. After the displacement, she participated in several educational and grant programs organized by the Media Initiatives Center, within the framework of which the produced media materials mainly concerned the problems of Artsakh residents.
Since September 2024, she has been studying in the "Multimedia" stream of the "Hetq Media Factory." Since December 2024, she has been a member of the "Center for International and Comparative Law" team.